Morbidity and Mortality Weekly Report, January 12, 2001 /
For an updated childhood immunization schedule see childschedule.pdf
Each year, CDC's Advisory Committee on Immunization Practices (ACIP) reviews the
recommended childhood immunization schedule to ensure that it remains current with changes
in manufacturers' vaccine formulations, revisions in recommendations for the use of
licensed vaccines, and recommendations for newly licensed vaccines. This report presents
the recommended childhood immunization schedule for 2001 (Figure 1)
and documents the changes that have occurred since the January 2000 publication (4).
For 2001, ACIP, the American Academy of Family Physicians, and the American Academy of
Pediatrics have added pneumococcal conjugate vaccine to the schedule (2) and have extended
the recommendation for the use of hepatitis A vaccine to include persons through age 18
years in selected geographic areas and in certain high-risk groups (3). Detailed
recommendations for using vaccines are available from the manufacturers' package inserts,
ACIP statements on specific vaccines, and the 2000 Red Book (5). ACIP statements
for each recommended childhood vaccine can be viewed, downloaded, and printed from CDC's
National Immunization Program World-Wide Web site, http://www.cdc.gov/nip/publications/ACIP-list.htm.
Pneumococcal Conjugate Vaccine
In February 2000, the Food and Drug Administration licensed a heptavalent pneumococcal
polysaccharide-protein conjugate vaccine (PCV) (Prevnar,* Wyeth Lederle Vaccines and
Pediatrics, Philadelphia, Pennsylvania) for use among infants and young children. All
children aged 2--23 months should receive four doses of PCV intramuscularly at ages 2, 4,
6, and 12--15 months. ACIP also recommends the vaccine for children aged 24--59 months who
are at increased risk for pneumococcal disease (e.g., children with sickle cell
hemoglobinopathies, human immunodeficiency virus infection, and other immunocompromising
or chronic medical conditions). For these children, ACIP recommends two doses of PCV
administered 2 months apart followed by one dose of a 23-valent pneumococcal
polysaccharide vaccine (PPV 23) administered two or more months after the second dose of
PCV. ACIP also recommends that PCV be considered for all other children aged 24--59
months, with priority given to children aged 24--35 months, American Indian/Alaska Native
and black children, and children who attend child-care centers. ACIP recommends one dose
of PCV for children in these groups. Additional information on the use of PCV can be found
in the ACIP statement (2).
Hepatitis A Vaccination Recommendation
ACIP continues to recommend hepatitis A vaccine (Hep A) for routine use in some states
and regions. For 2001, the recommendation has been extended to include adolescents through
age 18 years and for persons in certain high-risk groups (i.e., persons traveling to
countries where hepatitis A is moderately or highly endemic, men who have sex with men,
users of injectable and noninjectable drugs, persons who have clotting-factor disorders,
persons working with nonhuman primates, and persons with chronic liver disease). The
hepatitis A vaccine label is shaded on the 2001 Immunization Schedule to indicate its use
in selected states and regions, and for certain high-risk groups. Providers can contact
their local public health authority for the current recommendations for hepatitis A
vaccination in their community. Additional information on the use of Hep A can be found in
the ACIP statement (3).
Vaccine Information Statements
The National Childhood Vaccine Injury Act requires that all health-care providers give
to parents or patients copies of Vaccine Information Statements before administering each
dose of the vaccines listed in this schedule. Vaccine Information Statements, developed by
CDC, can be obtained from state health departments and CDC's World-Wide Web site, http://www.cdc.gov/nip/publications/VIS.
Instructions on use of the Vaccine Information Statements are available at http://www.cdc.gov/nip/publications/VIS/vis-Instructions.pdf.
- CDC. Poliomyelitis prevention in the United States: updated recommendations of the
Advisory Committee on Immunization Practices (ACIP). MMWR 2000;49(no. RR-5).
- CDC. Preventing pneumococcal disease among infants and young children: recommendations
of the Advisory Committee on Immunization Practices (ACIP). MMWR 2000;49(no. RR-9).
- CDC. Prevention of hepatitis A through active or passive immunization: recommendations
of the Advisory Committee on Immunization Practices (ACIP). MMWR 1999;48(no. RR-12).
- CDC. Recommended childhood immunization schedule---United States, 2000. MMWR 2000;49:35--8,47.
- American Academy of Pediatrics. Active and passive immunization. In: Pickering
2000 Red book: report of the Committee on Infectious Diseases. 25th ed. Elk Grove Village,
Illinois: American Academy of Pediatrics, 2000:1--81.
* Use of trade names and commercial sources is for identification only and does not
constitute endorsement by CDC or the U.S. Department of Health and Human Services.
Figure 1. Recommended childhood immunization schedule* -
United States, January-December 2001
Click to view a larger version of Figure 1
to view a larger version of Figure 1 Legend